Vocabulary and Grammar The following question is based on your reading of Macbeth, Act V. Lady Macbeth’s guilt causes her a great ____ of spirit.

Perturbation means disturbance or emotional agitation. Lady Macbeth’s guilt causes a great disturbance of spirit, so “perturbation” best completes the sentence. A harbinger is a warning or sign of something to come, while development and fortification do not fit the meaning.

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