Question 3 • R282: GR CA-Chemistry B (Grade Repair)
Aspirin is made by acetylating salicylic acid’s phenolic –OH group. This changes the molecule so its carboxyl group is less acidic: aspirin has a pKa of about 3.5, compared with about 3.0 for salicylic acid. Therefore, aspirin has lower acidity, choice C.
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