Select all that apply.Which of the following statements are true about the genetic disease phenylketonuria?

Without treatment, phenylketonuria (PKU) causes phenylalanine to build up in the body, which can damage the brain and impair development. It is usually detected through newborn screening, and managing PKU requires ongoing treatment, typically a carefully controlled diet, throughout life. Gene therapy and prenatal surgery are not standard treatments for PKU.

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