Manuel has started to become easily confused and has some memory loss. He is also frequently tired and has developed some swelling and a rash. What is most likely causing Manuel’s symptoms?

Lupus can affect multiple parts of the body, causing fatigue, swelling, and skin rashes. It can also affect the brain and nervous system, which may lead to confusion or memory problems. This combination makes lupus the most likely cause; lymphedema mainly causes swelling, while mononucleosis and lymphoma do not fit the full set of symptoms as well.

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